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GeneAssist™ siRNA Workflow Builder

Use this Pathway Atlas to:

View over 350 interactive pathway maps.
View and export a list of all genes, proteins, and products (Silencer® siRNAs & TaqMan® Gene Expression Assays) associated with a particular pathway.
Export an edited list of pathway-associated TaqMan Gene Expression Assays for upload into the TaqMan Express Plates and TaqMan Array ordering tools.
Click on a specific protein within a pathway map to view and order the siRNAs and Assays associated with that gene.

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Whats New!

We recently added new maps into the GeneAssist™ Pathway Atlas. Use the following links to access them directly.

1         Embryonic Cell Differentiation into Cardiac Lineages
2         Factors Promoting Cardiogenesis in Vertebrates
3         Human Early Embryo Development
4         Human Embryonic Stem Cell Pluripotency
5         Nanog in Mammalian ESC Pluripotency
6         Oct4 in Mammalian ESC Pluripotency
7         Transcriptional Regulatory Network in Embryonic Stem Cell

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1-9

1           14-3-3 and Cell Cycle Regulation
2           14-3-3 and Regulation of BAD Activity
3           14-3-3 Induced Apoptosis
4           14-3-3 Induced Intracellular Signaling
5           4-1BB Pathway
6           ABC Transporters in Cholestatic Hepatocytes
7           ABCG and ABCA Regulation of Sterol Metabolism
8           Actin Nucleation and Branching
9           Actin Nucleation by ARP-WASP Complex
10         Actin-Based Motility by Rho Family GTPases
11         Activation of cAMP-Dependent PKA
12         Activation of NF-KappaB by PKR
13         Activation of PKA through GPCR
14         Activation of PKC through GPCR
15         Agranulocyte Adhesion and Diapedesis
16         Agrin Interaction at Neuromuscular Junction
17         AHR Pathway
18         AIF Pathway
19         Airway Inflammation in Asthma
20         Airway Pathology in COPD
21         Akt Signaling
22         Aldosterone Signaling in Epithelial Cells
23         all-trans-Retinoic Acid Mediated Apoptosis
24         all-trans-Retinoic Acid Signaling in Brain
25         Alpha-Adrenergic Signaling
26         Alternative Complement Pathway
27         Alzheimer's Disease Pathway
28         AMPK Enzyme Complex Pathway
29         Androgen Signaling
30         Angiopoietin-TIE2 Signaling
31         Antigen Processing and Presentation by MHCs
32         Antioxidant Action of Vitamin-C
33         Antiproliferative Role of SSTR2
34         Apoptosis through Death Receptors
35         Apoptotic Pathways in Synovial Fibroblasts
36         Apoptotic Pathways Triggered By HIV1
37         APRIL Pathway
38         Assembly of RNA Polymerase-I Initiation Complex
39         Assembly of RNA Polymerase-II Initiation Complex
40         Assembly of RNA Polymerase-III Initiation Complex
41         Atherosclerosis-Disease Progression (No products, reference only)
42         ATM Pathway
43         Autoimmune Mechanism Causing Vitiligo
44         B-Cell Development
45         B-Cell Receptor Complex
46         Bacterial Meningitis
47         BAD Phosphorylation
48         BAFF Receptors in B-Cell Signaling
49         Base Excision Repair Pathway
50         BCR Pathway

51         BDNF Pathway
52         Beta-Adrenergic Signaling
53         Bitter Taste Signaling
54         Blood Coagulation Cascade
55         BMP Pathway
56         BRCA1 Pathway
57         Breast Cancer Regulation by Stathmin1
58         c-Myc and Apoptosis
59         C. pneumoniae Infection in Atherosclerosis
60         Calcium Mediated T-Cell Apoptosis
61         Calpain Protease Regulates Cellular Mechanics
62         cAMP Pathway
63         Cardiomyocyte Differentiation through BMP Receptors
64         Caspase Cascade
65         CCKBR-Gastrin Stimulated Signaling
66         CCR3 Pathway in Eosinophils
67         CCR5 Pathway in Macrophages
68         CD27 Pathway
69         CD28 Signaling in T-Helper Cell
70         CD40 Signaling
71         CDC42 Pathway
72         CDK5 Pathway
73         Cell Cycle Control by BTG Proteins
74         Cell Cycle Control of Chromosomal Replication
75         Cellular Apoptosis Pathway
76         Cellular Effects of Sildenafil
77         Cellular Immune Responses to HBV
78         Cellular Transformation by HTLV1
79         Ceramide Pathway
80         Checkpoint Comparative Pathways
81         Chemokine Signaling
82         Chks in Checkpoint Regulation
83         ChREBP Regulation in Rattus norvegicus
84         Chromatin Remodeling
85         Circadian Clock in Mammals
86         Classical Complement Pathway
87         Cleavage and Polyadenylation of Pre-mRNA
88         CMV and MAPK Pathways
89         CNTF Signaling
90         Complement Pathway
91         Cholera Infection
92         Colorectal Cancer Metastasis
93         CREB Pathway
94         CRHR Pathway
95         Crosstalk Between CARM1 and ESRs
96         CTL Mediated Apoptosis
97         CTLA4 Signaling
98         CXCR4 Pathway
99         Cyclins and Cell Cycle Regulation
100         Cytokine Network
101         Developmental Phases of Colorectal Cancer
102         DHA Signaling
103         DNA Damage Induced 14-3-3Sigma Signaling
104         DNA Methylation and Transcriptional Repression
105         DNA Repair Mechanism
106         Dopamine-DARPP32 Feedback onto cAMP Pathway
107         DR3 Signaling

108         DREAM Repression and Dynorphin Expression
109         DRPLA Pathway
110         DSB Repair by Homologous Recombination
111         DSB Repair by Non Homologous End Joining
112         EGF Pathway
113         eIF2 Pathway
114         Embryonic Cell Differentiation into Cardiac Lineages
115         Endocytic Trafficking of EGFR
116         Endothelin-1 Signaling Pathway
117         eNOS Signaling
118         Enteropathogenic E.coli Induced Diarrhea
119         EphB-EphrinB Signaling
120         Ephrin-Eph Signaling
121         EphrinA-EphR Signaling
122         Epithelial Adherens Junctions
123         Epithelial Tight Junctions
124         ER-Mediated Phagocytosis
125         ErbB Family Pathway
126         ErbB2-ErbB3 Heterodimers
127         ErbB4 Pathway
128         ERK Signaling
129         ERK5 Signaling
130         Erythrocyte Invasion by Plasmodium Merozoite
131         Erythropoietin Pathway
132         Estrogen Pathway
133         Estrogen-mediated S-Phase Entry
134         Exo-Erythrocytic Phase of Malaria Parasite (No products, reference only)
135         Extrinsic Prothrombin Activation Pathway
136         Factors Promoting Cardiogenesis in Vertebrates
137         FAK1 Signaling
138         Fanconi's Anaemia Pathway
139         Fas Signaling
140         Fc-EpsilonRI Pathway
141         Fc-Gamma-RIIB Signaling in B-Cells
142         Fc-GammaR Pathway
143         Fc-GammaR-Mediated Phagocytosis in Macrophages
144         FGF Pathway
145         FLT3 Signaling
146         fMLP Pathway
147         G-AlphaI Signaling
148         G-AlphaQ Signaling
149         G-AlphaS Signaling
150         G-Beta Gamma Signaling
151         G-Protein Signaling through Tubby Protein
152         G1-S Phase Transition
153         G12-G13 in Cellular Signaling
154         G2-M Phase Transition
155         GADD45 Pathway
156         GDNF-Family Ligands and Receptor Interactions
157         Germ Cell-Sertoli Cell Junction Dynamics
158         GHRH Signaling
159         GITR Pathway
160         Glucocorticoid Receptor Signaling
161         Glioblastoma Multiforme
162         Glioma Invasiveness

163         GnRH Signaling
164         GPCR Pathway
165         Granulocyte Adhesion and Diapedesis
166         Granzyme Pathway
167         Granzyme-A Pathway
168         Granzyme-B Pathway
169         Growth Hormone Signaling
170         GSK3 Signaling
171         Guidance Cues and Growth Cone Motility
172         H. pylori Activated Signaling
173         Hair Growth Cycle (No products, reference only)
174         Hedgehog Signaling in Mammals
175         Hepatic ABC Transporters
176         HGF Pathway
177         HIF1Alpha Pathway
178         HMGB1 Pathway
179         HOP Signaling
180         HSV1 Latent Infection
181         Human Early Embryo Development
182         Human Embryonic Stem Cell Pluripotency
183         Huntingtin Comparative Pathway
184         Huntington Disease Pathway
185         ICos-ICosL Pathway in T-Helper Cell
186         IGF1R Signaling
187         IL-1 Pathway
188         IL-10 Pathway
189         IL-2 Gene Expression in Activated and Quiescent T-Cells
190         IL-2 Pathway
191         IL-22 Pathway
192         IL-3 Pathway
193         IL-4 Pathway
194         IL-6 Pathway
195         IL-9 Pathway
196         Inhibition of Angiogenesis by TSP1
197         Inhibition of Matrix Metalloproteinases
198         Inhibition of Ribosome Biogenesis by p14(ARF)
199         Inhibition of Ribosome Biogenesis by p19(ARF)
200         ILK Signaling
201         iNOS Signaling
202         Insulin Receptor Pathway
203         Integrin Pathway
204         Interferon Pathway
205         Internalin Pathway
206         Intracellular Calcium Signaling
207         Intraepithelial Neoplasia of Pancreas
208         Intrinsic Prothrombin Activation Pathway
209         IP3 Pathway
210         ITK and TCR Signaling
211         JAK-STAT Pathway
212         JNK Pathway
213         LDL Oxidation in Atherogenesis
214         LDLR Biosynthesis and Transport
215         Lectin Induced Complement Pathway
216         Life Cycle of Plasmodium falciparum (No products, reference only)
217         Lipid Antigen Presentation by CD1

218         LPS Stimulated MAPK Signaling
219         LT-BetaR Pathway
220         Macrophage Differentiation and Growth Inhibition by METS
221         MAPK Family Pathway
222         MAPK Signaling
223         Mechanism of Anthrax Toxins
224         Mechanism of Botulinum Toxin
225         Melanocyte Development and Pigmentation
226         Melatonin Signaling
227         Metabolic States and Circadian Oscillators
228         MIF Action Through Endocytic Pathway
229         MIF Mediated Glucocorticoid Regulation
230         MIF Regulation of Innate Immune Cells
231         Mismatch Repair Pathway in Eukaryotes
232         Mitochondrial Apoptosis
233         Mitochondrial Protein Import Pathways
234         Mitotic Roles of Polo-Like Kinase
235         MNAR-PELP1 and Estrogen Receptor Interaction
236         MODY (Maturity-Onset Diabetes of Young)
237         Molecular Mechanisms of Cancer
238         MSP-RON Signaling
239         mTOR Pathway
240         Mucosal Healing through Trefoil Factors
241         Murine METS Protein Signaling
242         Murine MSP-STK Signaling
243         Muscular Dystrophies and Dystrophin-Glycoprotein Complex
244         Nanog in Mammalian ESC Pluripotency
245         Netrin Signaling
246         Neuropathic Pain - Signaling in Dorsal Horn Neurons
247         NF-KappaB (p50-p65) Pathway
248         NF-KappaB Activation by EBV
249         NF-kappaB Activation by Viruses
250         NF-KappaB Family Pathway
251         NFAT and Cardiac Hypertrophy
252         NFAT in Immune Response
253         NFAT Signaling and Lymphocyte Interactions
254         NGF Pathway
255         NgR-p75(NTR)-Mediated Signaling
256         NK1R-mediated Non-Apoptotic PCD
257         nNOS Signaling at Neuronal Synapses
258         nNOS Signaling in Skeletal Muscle
259         Notch Signaling
260         NTHi-Induced Signaling
261         Nuclear Receptor Activation by Vitamin-A
262         Nucleotide Excision Repair Pathway
263         Nur77 Signaling in T-Cell
264         Nur77-Induced AICD in Macrophage
265         Oct4 in Mammalian ESC Pluripotency
266         Olfactory Signal Transduction
267         Olfactory System (No products, reference only)
268         OSM Pathway
269         OX40 Pathway

270         P2Y Receptor Signaling
271         p38 Signaling
272         p53 Mediated Apoptosis
273         p53 Signaling
274         p70S6K Signaling
275         PACAP Signaling
276         PAK Pathway
277         Pancreatic Adenocarcinoma
278         Parkinson's Disease Pathway
279         Pathogenesis of ALS
280         Pathogenesis of Gliomas
281         Pathogenesis of Helicobacter pylori Infection
282         Pathogenesis of Multiple Sclerosis
283         Pathogenesis of Rheumatoid Arthritis
284         Paxillin Interactions
285         PDGF Pathway
286         PEDF Induced Signaling
287         PGC1Alpha Pathway
288         Phagocytosis of Microbes
289         Phospholipase-C Pathway
290         PI3K Signaling
291         PI3K Signaling in B-Lymphocyte
292         PKA Signaling
293         PKC-Theta Pathway
294         PKR Pathway
295         Polyamine Regulation in Colon Cancer
296         PPAR Pathway
297         Presenilin-Mediated Signaling
298         Prion Pathway
299         Prolactin Signaling
300         Protein Acetylation and Deacetylation
301         PTEN Pathway
302         Rac1 Pathway
303         Ran Pathway
304         RANK Pathway
305         RANK Signaling in Osteoclasts
306         Rap1 Pathway
307         RAR-Alpha-PML Fusion During APL
308         RAR-Gamma-RXR-Alpha Degradation
309         Ras Pathway
310         Reelin Pathway (Cajal-Retzius cells)
311         Regulation of eIF4 and p70S6K
312         Relaxin Pathway
313         Remodeling of Adherens Junctions
314         Renin-Angiotensin Pathway
315         Repair of 8-oxoG by hOGG1
316         Repair of O6-MeG by MGMT
317         Repair of Thymine Dimers
318         Repair of Uracil Residues
319         Rho Family GTPases
320         RhoA Pathway
321         RhoGDI Pathway
322         RNAi Pathway
323         Rotavirus Induced Diarrhea

324         S-1P Stimulated Signaling
325         Salmonella Infection
326         Semaphorin Signaling
327         Sertoli-Sertoli Cell Junction Dynamics
328         Shigella Invasion
329         Signaling by Slit
330         Signaling in Gap Junctions
331         Signaling Involved in Cardiac Hypertrophy
332         siRNA Pathway
333         siRNA Pathway in Nematode and Mammal
334         SMAD Signaling Network
335         SOCS Pathway
336         Sperm Motility
337         Sphingolipid Metabolism and Apoptosis
338         Spliceosomal Splicing Cycle
339         STAT3 Pathway
340         SUMO Pathway
341         Sweet Taste Signaling
342         T-Cell Receptor and CD3 Complex
343         TCR Signaling
344         Tec Kinases Signaling
345         Telomerase Components in Cell Signaling
346         Telomere Extension by Telomerase
347         TGF-Beta Pathway
348         THC Differentiation Pathway
349         Thrombin Signaling
350         Thrombopoietin Pathway
351         TLR-TRIF Pathway
352         TNF Signaling
353         TNF Superfamily Pathway
354         TNF-Induced Apoptosis Implicating Sphingolipids
355         TNFR1 Pathway
356         TNFR2 Pathway
357         TOB in Osteoblast Signaling
358         TOB in T-Cell Signaling
359         Toll Comparative Pathway
360         Toll-Like Receptors Pathway
361         Tooth Development and Decay(No products, reference only)
362         TRAF Pathway
363         Transcription of mRNA
364         Transcription of rRNA
365         Transcription of tRNA
366         Transcriptional Regulatory Network in Embryonic Stem Cell
367         TRAIL Pathway
368         TREM1 Pathway
369         Transendothelial Migration of Leukocytes
370         TRKA Signaling
371         Tumoricidal Effects of Hepatic NK Cells
372         TWEAK Pathway
373         Ubiquitin-Proteasome Dependent Proteolysis
374         UPA-UPAR Pathway
375         UVA-Induced MAPK Signaling
376         UVB-Induced MAPK Signaling
377         UVC-Induced MAPK Signaling
378         Vav Signaling in T-Lymphocyte
379         VEGF and S-1P Signaling
380         VEGF Family Ligands and Receptor Interactions
381         VEGF Pathway
382         Virus-Induced Airway Inflammation
383         Visual Cycle in Retinal Rods
384         Vitamin-C Transport
385         WNT Signaling
386         Yersinia Infection

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