New Silencer® siRNA Libraries

Expedite Gene Function Analysis

Ambion Silencer® siRNA Libraries feature combinations of Silencer Pre-designed siRNAs and, when available, Silencer Validated siRNAs in 96-well or 384-well plates The design of each siRNA has been carefully optimized to provide potent and specific silencing. Indeed, the siRNA selection process yields siRNAs that are effective at low concentrations, enabling screening experiments at 30 nM siRNA or lower, which minimizes reagent costs and off-target effects. Genomewide collections of siRNAs are available for human and mouse for large-scale screening projects, while gene function-based and custom subsets are available for more focused studies.

Several ready-to-ship libraries are available and are shown at right. These libraries contain 0.25 nmol of each siRNA, sufficient for 100 transfections (at 25 nM siRNA, 100 µL transfection volume). The siRNAs are supplied dried in the wells of 96-well plates; one column of each 96-well plate is left empty to allow addition of controls at the time of use. The libraries are delivered with full siRNA sequence information plus results from any validation experiments done using the included siRNAs.

Libraries to these or other lists of human, mouse, or rat genes can also be provided with 1, 2, or 5 nmol of each siRNA. Custom formatting is available with these larger sizes.

Email us or explore the website for more details, additional libraries, customization, and pricing.

For Research Use Only. Not for use in diagnostic procedures.