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siRNA and RNAi resource
Introduction to miRNAs

Definition and Overview

miRNA Processing

miRNA Function

Expression & Targets

Exploration: Introduction to microRNAs

Ambion Resources

miRNA Database
GeneAssist™ miRNA Workflow Builder

miRNA Research Guide (PDF)
[Request a hardcopy]

Workflow: miRNA Expression Analysis

New Ambion Articles

Accurate, Sensitive Quantitation of microRNAs from FFPE Tissues

Variation of microRNA Profiles in Normal vs. Cancerous Hepatocytes

Your Data: The Role of microRNAs in Cervical Cancer

MicroRNA Analysis—Start Here

A Streamlined Workflow for Whole Genome Discovery and Profiling of Small RNAs

[more...]

Ambion Products

All miRNA Products

Product Citations

NEW Product!
TaqMan® MicroRNA Cells-to-CT™ Kit
The TaqMan MicroRNA Cells-to-CT Kit makes it possible to perform microRNA (miRNA) expression profiling directly from cultured cells without RNA purification. The kit is the first to offer a simple, complete workflow for miRNA expression analysis from a few samples, or it can easily be incorporated into automated, high throughput applications.

Ambion Publications

Johnson CD, Esquela-Kerscher A, Stefani G, Byrom M, Kelnar K, Ovcharenko D, Wilson M, Wang X, Shelton J, Shingara J, Chin L, Brown D, Slack FJ. The let-7 MicroRNA Represses Cell Proliferation Pathways in Human Cells. Cancer Res. 2007 Aug 15;67(16):7713-22. [Abstract]

Shingara J, Keiger K, Shelton J, Laosinchai-Wolf W, Powers P, Conrad R, Brown D, Labourier E. An optimized isolation and labeling platform for accurate microRNA expression profiling. RNA. 2005 Jul 25; [Epub ahead of print] [Abstract]

Johnson SM, Grosshans H, Shingara J, Byrom M, Jarvis R, Cheng A, Labourier E, Reinert KL, Brown D, Slack FJ. RAS is regulated by the let-7 microRNA family. Cell. 2005 Mar 11;120(5):635-47. [Abstract]

Cheng AM, Byrom MW, Shelton J, Ford LP. Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res. 2005 Mar 1;33(4):1290-7. [Abstract]

External Web Resources

miRBase: The Home of microRNA Data

A Uniform System for microRNA Annotation


miRNA in the News

MicroRNAs Help Control HIV Life Cycle - 6/26/09

New Strategy Rapidly Reveals Targets for MicroRNA Gene Regulation - 6/18/09

Mean New MicroRNA Data Analysis Method Gives Sharper Results - 6/16/09

RNA Snippet Suppresses Spread of Aggressive Breast Cancer - 6/16/09

MicroRNAs Grease The Cell's Circadian Clockwork - 6/1/09

MicroRNA Regulation of Tumor-Killing Viruses Avoids Unwanted Viral Pathology - 5/22/09

MiR-196a Promotes the Metastases of Tumors - 5/14/09

Researchers Find Snippet of RNA That Helps Make Individuals Remarkably Alike - 5/6/09

Throwing the Micro Switch: MicroRNA May Link Smoking Risk Gene to Neurobiology of Addiction - 4/23/09

Genetic Variations in MiRNA Processing Pathway and Binding Sites Help Predict Ovarian Cancer Risk - 4/19/09

Small RNAs Can Play Critical Roles in Male Infertility/contraception - 4/10/09

Nuclear Hormone Receptors, MicroRNAs Form Developmental Switch - 4/3/09

 
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