Have a suggestion for a new link? E-mail the editor. General Resources and Tools for the Researcher
- Medline
Workbench - Search Evaluated Medline, PubMed or AbstractsFinder
all from the same page. You can also sign up to receive a free daily
update of your PubMed queries via e-mail and get access to a number
of free online journals.
- NIH
Office of Extramural Research - Stats and information about NIH
grants, as well as a searchable database (CRISP) of federally supported
research projects.
- WebElements
Periodic Table - An interactive periodic table. Includes a
short background and description, along with uses, electronic properties,
physical properties, and crystal structures for each element. There
are even nerdy science cartoons and a few short movies
General Life Science Resources
- Art's
Biotech Resources - An outstanding metalist of molecular biology,
biochemistry, biophysics and bioinformatics sites. Includes links
to protocols, tutorials, software and databases.
- The
Bio Sciences Virtual Library - A metalist of resources categorized
by life science field.
- biocompare - "The
buyer's guide for the life scientist." Has product reviews (including
Ambion products) and facilitates comparisons of kits and reagents from
several different companies.
- Biology
Links - An extensive list of links to biochemistry, molecular
biology and immunology resources from the Harvard University Dept
of Molecular and Cellular Biology.
- Cell & Molecular
Biology Online - An annotated metalist of resources for molecular
and cellular biologists. Includes links to protocols, codon usage
and periodic tables, and education resources.
- DNA
Learning Center - An excellent educational resource, geared toward
students and nonscientists, for information about genes. Check out DNA
From the Beginning, an animated primer on the basics of DNA,
genes and heredity.
- GenomeBiology.com -
An online journal focusing on genomics and "biology for the post-genomics
era."
- Indiana
University Bio Archive - A collection of software (free!) and
data for molecular biology and related areas.
- Linscott's
Directory - A resource of more than 100,000 different reagents
used in Biomedical Research, from more than 400 different suppliers
and distributors.
- National
Center for Biotechnology Information (NCBI) - A national resource
for molecular biology information from the National Library of Medicine
and NIH. This is the home of the popular Entrez databases. You can
search PubMed, submit your sequence to GenBank, perform BLAST searches
and get genome information on a number of different organisms.
- Primer
3 - An interactive, forms-based tool for designing primers from
an input DNA sequence.
- PrimerBank - A public resource for PCR primers. These primers are designed for gene expression detection or quantification (real-time PCR). PrimerBank contains about 180,000 primers covering most known human and mouse genes.
- The
Southwest Biotechnology and Informatics Center (SWBIC) - A dizzying
number of links to research tools and databases related to the life
sciences.
Nucleic Acid and Protein Sequence and Structure Databases
- Baylor
College of Medicine Search Launcher - Search multiple databases
with a single input nucleic acid or protein sequence. You can also
get secondary structure predictions based on sequences.
- Biology
Workbench - A comprehensive and user-friendly suite of online
protein and nucleic acid bioinformatics software. Using these tools,
you can search popular nucleic acid and protein sequence databases
and then analyze the data with a variety of analysis and modeling
tools.
- Molecules
R Us Utility - A searchable PDB database of protein and nucleic
acid structures.
- Single
Nucleotide Polymorphisms for Biomedical Research - A public
database of single nucleotide polymorphisms (SNPs) within the human
genome.
Molecular Biology Protocol Collections and Techniques
Forums
- Molecular
Biology Protocols - A collection of basic protocols on the most
popular molecular biology techniques. From the Northwest Fisheries
Science Center.
- Molecular
Biology Techniques Forum - A forum for reader-submitted techniques,
tips and questions concerning molecular biology. Run by the Northwest
Fisheries Science Center.
-
MolecularStation
- Information on molecular biology, including methods
and protocols, bioinformatics, and the latest science news. Also a forum for discussion of molecular research techniques.
- PCR
and Multiplex PCR: Guide and Troubleshooting - A very informative
guide to PCR, including discussions of parameters influencing PCR,
troubleshooting advice and PCR applications. Also includes links
to a discussion of FISH (fluorescent in situ hybridization) and CCK
(color changing karyotyping).
- The
Polymerase Chain Reaction (PCR) Jump Station - Bills itself as "the
ultimate Web page for information and links on all aspects of the
Polymerase Chain Reaction (PCR)," which is actually a pretty
good description of its offerings.
- Protocol
Online - A collection of user-written protocols in many research
areas, including molecular biology. Includes a techniques forum,
e-mail broadcast of queries, and free automated PubMed searches with
e-mail notification.
- Protocols
for Recombinant DNA Isolation, Cloning and Sequencing - An extensive
protocol collection of common methods (mostly DNA related) used in
molecular biology laboratories. The appendix contains
useful information tidbits, such as units and formulas, DNA mobility
in gels and consensus sequences in nucleic acids. From Bruce Roe's
lab at the University of Oklahoma.
RNA Related Resources
- Biomolecules
Lecture on RNA Structure - This "lecture" from Jim
Nolan includes an overview of RNA structure and useful tables on
RNases and chemicals used to probe RNA structure.
- The Comparative RNA Web
Site - A compilation of information on comparative structure
models, nucleotide frequency and conservation, and secondary structure
diagrams for a wide variety of RNAs. From the Gutell lab at the University
of Texas. Requires registration (free, but multi-step).
- Microarray
FAQ - A basic introduction to microarrays, including what they
are, how they are made, and why they are useful.
- RNA -
The official journal of the RNA Society.
- RNA
Analysis Tools - A list of tools to predict RNA secondary structure,
as well as distances, specific heat and energy of RNA secondary structures.
- The
RNA Society - A FASEB organization. Get information about the
RNA Society annual meeting and upcoming events.
- RNA
WebRing - Provides links to academic labs and companies that
have an interest in virtually any aspect of RNA research, including
transcription, processing, export, stability and editing.
- The
RNA World at IMB-Jena - An impressive metalist of RNA related
topics on the Web. Includes links to structure and sequence databases,
protocols, software and tutorials.
- Stanford
Microarray Database - A database of normalized gene expression
data from microarray experiments.
- TRANSFAC
(The Transcription Factor Database) - Information on transcription
factors, such as classifications, recognition sequences, amino
acid sequences and references. You can search for transcription
factor recognition sites in your DNA sequences.
RNA Clubs
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