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siRNA and RNAi resource
New to RNAi? Start Here!

The Mechanism of RNA Interference

Overview of RNA Interference

RNAi: A "How To" for New Users

Getting Started with RNAi

siRNA Decision Tree

Workflow: Using siRNAs to Delineate Gene Function

Ambion Resources

siRNA Database (New version)

siRNA Design Tools

siRNA Delivery Resource

In Vivo siRNA Resource

RNAi Research Guide (PDF)
[Request a hardcopy]

siRNA Screening Guide
[Request a hardcopy]

New Ambion Articles

Getting Started with RNAi In Vivo

Calculating Gene Expression Changes and Variability in siRNA Experiments

Reduced siRNA Concentrations Lead to Fewer Off-Target Effects

Experimental Variability and Replicates in siRNA Experiments

Understanding Calculations for siRNA Data: Percent Remaining Gene Expression and Percent Knockdown

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Ambion Products

siRNA Products & Services

All RNAi Products

NEW!
Silencer® Select siRNAs
Next Generation Ambion siRNAs
More potent--Fewer off target effects--More consistent phenotypes

Ambion Publications

High-throughput RNAi screening in vitro: From cell lines to primary cells.
Ovcharenko D, Jarvis R, Hunicke-Smith S, Kelnar K, Brown D. (2005) RNA. 11:985-993. [Abstract]

The ins and outs of RNAi in mammalian cells.
Banan M, Puri N. (2004) Curr Pharm Biotechnol.5(5):441-50. [Abstract]

Webcasts

Next Generation siRNA Technology to Make Your Silencing Roar
Susan Magdaleno, PhD November 2007


siRNA Library User Meeting
Darmstadt, Germany
October 22, 2008

[More Info ]

RNAi in the News

RNA Interference Plays Bigger Role than Previously Thought Biocompare 9/17/08

Designer RNA Fights High Cholesterol, Researchers Find Biocompare 8/11/08

Researchers Halt Spread of HIV with RNAi Biocompare 8/8/08

Scientists Discover Small RNAs That Regulate Gene Expression and Protect the Genome Biocompare 5/13/08

 
LSIA RNAi Award

Ambion Press Releases

Ambion to Provide MitoCheck Consortium a Genome-Wide siRNA Library - 7/12/05

Ambion Kinase siRNA Library Used in Key Cellular Trafficking Study - 7/7/05

 
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