Trademarks

Registered Trademarks: Ambion, Armored RNA, BrightStar, FirstChoice, MAXIscript, MEGAscript, mMESSAGE mMACHINE, NorthernMax, PROTEINscript, RETROscript, RNAlater, RNAqueous, RNaseAlert, RNaseZap, Silencer, Strip-EZ, The RNA Company, and ULTRAhyb are registered trademarks of Ambion.

Trademarks: ActivePro, Agarose-HR, Agarose-LE, Agarose-LM, Anti-miR, ArrayControl, ArrayScript, BioDetect, CellReady, Cells-to-cDNA, Cells-to-Signal, Century, Competimer, CU minus, Decade, DECAprime, DECAtemplate, Direct Protect, DNAclear, DNA-free, DNaseAlert, DNAZap, ElectroZap, EndoFree RT, flashPAGE, GLOBINclear, GlycoBlue, HybSpeed, the "Just Say No to RNase" logo, KDalert, KinaseMax, LandMark, LeukoLOCK, MagMAX, MEGAclear, MEGAshortscript, MELT, MessageAmp, MICROBEnrich, MICROBExpress, MicroPoly(A)Purist, Millennium Markers, mirVana, MODIscript, mRNAlocator, NeoFX, NucAway, PARIS, Poly(A)Pure, Poly(A)Purist, Pre-miR, pSEC, pSilencer, QuantumRNA, RecoverAll, Retic Lysate IVT, RiboPure, RNA Polymerase-Plus, RNase Cocktail, RNAsecure, "RNase-Free with Ambion", RNAwiz, RPA II, RPA III, siPORT, siPORTer, SlideHyb, StripAble, Strip-EZ, SUPERase•In, The RNAi Company, The siRNA Company, ToTALLY RNA, TotalPrep, TRIPLEscript, and TURBO DNase are trademarks of Ambion.

Armored RNA is a registered trademark of Ambion, Inc. and Cenetron Diagnostics, LLC.

ABI PRISM is a registered trademark of PerkinElmer Corporation. Atlas is a trademark of BD Biosciences Clontech. Biomek is a registered trademark of Beckman Coulter, Inc. CDP-Star is a registered trademark of Tropix. Cy and CyDye are trademarks of Amersham Biosciences. Eppendorf is a registered trademark of Brinkmann Instruments, Inc. GeneFilter is a registered trademark of Research Genetics. MultiPROBE is a registered trademark of PerkinElmer Corporation. Oxford Benchmate is a registered trademark of Sherwood Medical Industries. Pipetman is a registered trademark of Gilson Medical Electronics. Proline is a registered trademark of Biohit Corporation. RNasin is a registered trademark of Promega Corporation. SuperTaq is a trademark of Enzyme Technologies.

Patents and Licensing

Anti-miR™ miRNA Inhibitor, Armored RNA®, ArrayScript™, Cells-to-cDNA™ II, Cells-to-Signal™, DNA-free™, GLOBINclear™, HybSpeed™ RPA, LCM Staining, LeukoLOCK™, MagMAX™, MEGAscript®, MEGAscript® RNAi, MEGAshortscript™, MELT™, MessageAmp™ II-Bacteria, MicroPoly(A)Purist™, mirVana™ miRNA Detection, mirVana™ miRNA Isolation, mirVana™ miRNA Labeling, mMESSAGE mMACHINE®, mMESSAGE mMACHINE® T7 Ultra, Poly(A)Purist™, Poly(A)Purist™ MAG-96 Automated, Pre-miR™ miRNA Precursor, QuantumRNA™ 18S and ß-Actin Internal Standards, Recombinant DNase, RecoverAll™, RNAlater®, RNAlater®-ICE, RNAsecure™, RNase III for siRNA generation, RPA II™, RPA III™, RT-PCR Competitor Construction, Silencer™ siRNA Cocktail (RNase III), Silencer™ siRNA Construction, Silencer™ siRNA Labeling, siPORTer™-96, Strip-EZ™, SUPERase•In™, TRIPLEscript™, TURBO DNase™, and TURBO DNA-free™ technologies are covered by patents pending and/or U.S. patents owned by Ambion, Inc.

Armored RNA® is a patented technology jointly developed by Ambion, Inc. and Cenetron Diagnostics, LLC. U.S. Patent Nos. 5677124, 5919625, 5939262, 6214982, 6399307, AU 729601 and patents pending.

CDP-Star® is manufactured under U.S. Patent No. 5330900.

Cy™3 containing products or portions thereof are manufactured under license from Carnegie Mellon University and are covered by U.S. Patent No. 5268486.

pSilencer™ Vectors: Licensing Information

Psoralen-Biotin is manufactured by Schleicher and Schuell for Ambion, and its use for labeling nucleic acid probes is covered by U.S. Patent No. 4599303.

RNaseAlert® was developed in collaboration with Integrated DNA Technologies and is the subject of a US Patent Application submitted by Integrated DNA Technologies.

Silencer™ Express siRNA Expression Cassette Kits: Licencing Information

Silencer™ siRNA Construction Kit: Ambion has been granted rights by the Massachusetts Institute of Technology to U.S. Patent Applications 60/265232, 09/821832, and PCT/US01/10188, RNA Sequence-Specific Mediators of RNA Interference.

Silencer™ siRNA Labeling Kits contain Cy™3 and fluorescein labeling reagents manufactured for Ambion by Mirus Corporation.

siPORT™ Amine is manufactured for Ambion by Mirus.

TRI Reagent® is a registered trademark of Molecular Research Center, Inc. TRI Reagent® is a subject of US Patent 5,346,994.

Notice to Purchasers of Cells-to-cDNA™ II, EndoFree RT™, FirstChoice® RLM-RACE Kit, or QuantumRNA™ Internal Standards:
These products are optimized for use in the Polymerase Chain Reaction (PCR) covered by patents owned by Hoffman-La Roche, Inc. and F. Hoffman-La Roche Ltd. (Roche). No license under these patents to use the PCR process is conveyed expressly or by implication to the purchaser by the purchase of these products. A license to use the PCR process for certain research and development activities accompanies the purchase of certain reagents from licensed suppliers when used in conjunction with an authorized thermal cycler, or is available from the Perkin-Elmer Corporation. Further information on purchasing licenses to practice the PCR process may be obtained by contacting the Director of Licensing at The Perkin-Elmer Corporation, 850 Lincoln Centre Drive, Foster City, CA 94404 or at Roche Molecular Systems, Inc., 1145 Atlantic Avenue, Alameda, CA 94501.

Notice to Purchasers of SuperTaq™ & SuperTaq Plus™
SuperTaq™ is made by Enzyme Technologies Limited and sold under licensing arrangements with F. Hoffmann-La Roche Ltd., Roche Molecular Systems, Inc. and the Perkin-Elmer Corporation. Ambion is a distributor of Enzyme Technologies Limited.

Limited License:
A license under U.S. Patent Nos. 4683202, 4683195, 4965188 and 5075216 or their foreign counterparts, owned by Hoffman-La Roche and F. Hoffmann-La Roche Ltd. ("Roche"), has an up-front fee component and a running-royalty component. The purchase price of this product includes limited nontransferable rights under the running-royalty component to use only this amount of the product to practice the Polymerase Chain Reaction ("PCR") and related processes described in said patents solely for the research and development activities of the purchaser when this product is used in conjunction with a thermal cycler whose use is covered by the up-front fee component. Rights to the up-front fee component must be obtained by the end user in order to have a complete license. These rights under the up-front fee component may be purchased from Perkin-Elmer or obtained by purchasing an Authorized Thermal Cycler. No right to perform or to offer commercial services of any kind using PCR, including without limitation reporting the results of purchasers activities for a fee or other commercial consideration, is hereby granted by implication or estoppel. Further information on purchasing licenses to practice the PCR process may be obtained by contacting the Director of Licensing at Perkin-Elmer Corporation, 850 Lincoln Centre Drive, Foster City, California 94494 or at Roche Molecular Systems, Inc. 1145 Atlantic Avenue, Alameda, California 94501.

Warranty and Liability

Ambion is committed to providing the highest quality reagents at competitive prices. Ambion warrants that the products meet or exceed the performance standards described in the product specification sheets. If you are not completely satisfied with our products, our policy is to replace the product or credit the full purchase price, shipping and handling. No other warranties of any kind, expressed or implied, are provided by Ambion. Ambion's liability shall not exceed the purchase price of the product. Ambion shall have no liability for direct, indirect, consequential, or incidental damages arising from the use, results of use, or inabilty to use its products.

Hazardous Substances

Some of the products listed on this web site are known to be toxic or cancer-suspect agents and are so labeled. Such products must be handled with extreme caution. Many other products have not been tested for toxicity. The absence of a specific warning should not be interpreted to mean that the products have been proven to be nontoxic. Material Safety Data Sheets are sent with all products.

Intended Use

All products sold by Ambion are intended for research use only, unless otherwise indicated. These products are not suitable for diagnostic or drug purposes nor are they suitable for administration to humans or animals.