• Total RNA from pairs of individual human tumor & normal adjacent tissues
  
  
• Examine gene expression within individual tumor samples
  
  
• Multiple samples from a variety of tumor types
  
  

With the emergence of more sophisticated techniques for gene expression analysis (e.g. microarray analysis, real-time RT-PCR), the quality of the RNA samples being studied becomes increasingly critical. As The RNA Company^®, Ambion is committed to providing the highest quality RNA available. To achieve this goal it is necessary to understand what "high quality RNA" truly means with respect to various downstream applications. Intactness of mRNA, genomic DNA contamination, presence/absence of enzymatic inhibitors, and ribosomal RNA contamination in poly(A) preparations are all important aspects of RNA quality. As we continue to gain a better understanding of how these factors affect downstream applications, we will strive to ensure that our FirstChoice RNA products exceed the requirements for even the most stringent applications.

FirstChoice Tumor/Normal Adjacent Tissue RNA pairs include 5 µg of total RNA isolated from an individual tumor and the normal adjacent tissue (NAT). Each product is derived from a single donor and has not been pooled with other RNA. Ambion offers a variety of Tumor/NAT pairs for each tumor/tissue type. Note: Due to the nature of the samples, ovary and lymphoma NATs are not always from the same individual as the tumor tissue. Also, because of the small size of each tumor, availability of RNA from each individual tumor/NAT pair is limited.

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