RPA Grade RNase A is intended for those who desire to use RNase A alone in ribonuclease protection assays instead of the usual mixture of RNases A and T1. It is free of DNase and nicking activities. This product is equivalent to molecular biology grade RNase A from other suppliers.

Affinity Purified RNase A is intended for critical applications when the absence of DNase and other nonspecific nuclease activities is essential. RNase A is an endonuclease that specifically cleaves 3' of U and C residues. Note: This preparation contains RNase B, a carbohydrate isoform of RNase A.

Quality Control
RNase A is rigorously tested for contaminating nonspecific endonuclease, exonuclease, and protease activity. In addition, for RNase A (RPA Grade) functionality is determined in a standard RPA III™ (Cat #AM1414) reaction.

Ambion now offers an RNA-Grade RNase A preparation for use in RNA structure/function experiments. For more information, see RNA-Grade Ribonucleases.

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